Pan-European value set for the EQ-5D-3L
A single value set that combines health state preferences from multiple European countries to estimate quality of life for use in health technology assessments across Europe.
At a glance
Use when
Conducting multinational or EU-level HTA; when country-specific value sets are unavailable; for comparative economic evaluations across Europe
Avoid when
Local value sets exist and local preferences are prioritized; when cultural or healthcare system differences are expected to strongly influence health valuations
Inputs
EQ-5D-3L health state descriptions (five dimensions with three levels each)
Outputs
Health state utility values on a scale typically ranging from 0 (death) to 1 (full health), allowing for negative values (worse than death)
How it works
A pan-European value set for the EQ-5D-3L was developed by synthesizing published time trade-off (TTO) data from 12 European countries. Utility values for all 243 health states were simulated using national value set coefficients. An OLS regression model with interaction terms was selected based on goodness-of-fit. Population weighting was tested but had minimal impact.
- Project
- PECUNIA
- Funding
- Horizon 2020
- Project status
- Completed 2021
- HTA domains
- Costs & Economic Evaluation
- Categories
- HRQoL
- Technology
- Non-specific
- Assumptions
- National EQ-5D-3L valuation studies are methodologically comparable; preferences across Europe are sufficiently similar to justify aggregation; simulated utilities based on published coefficients accurately reflect original data
- Strengths
- Enables consistent economic evaluations across Europe; fills gap for countries without national value sets; model is transparent and easily updatable with new national data
- Limitations
- May mask important cultural or regional differences in health preferences; relies on simulated data rather than primary valuation studies; does not replace need for local validation
- Also known as
- Pan-European EQ-5D-3L value set
Questions this answers
- › What is the average health-related quality of life weight for a given EQ-5D-3L health state in Europe?
- › How can I calculate utility values for economic evaluations at the European level?
- › Can I use this value set if my country doesn't have its own EQ-5D-3L valuation?
- › Is it possible to combine national EQ-5D value sets into a single European one?
- › Does population weighting affect the pan-European utility values?
- › How comparable are EQ-5D valuation studies across European countries?
Related methods
Similar by meaning
Beta record. Generated from the primary source via AI extraction and independent audit, pending final human review.