EQ-5D-Y-3L value sets
This is a set of values that helps measure how different health conditions affect the quality of life of children and adolescents, specifically from the perspective of a 10-year-old child. It was developed for use in Slovenia but is the first such set available globally for the EQ-5D-Y-3L questionnaire.
At a glance
Use when
Conducting economic evaluations involving children and adolescents in Slovenia or similar settings; when EQ-5D-Y-3L data need to be converted into QALYs
Avoid when
When child self-reported preferences are required; in populations with significantly different cultural values regarding child health; for use outside pediatric populations
Inputs
EQ-5D-Y-3L health state descriptions (five dimensions: mobility, self-care, usual activities, pain/discomfort, anxiety/depression, each with three severity levels)
Outputs
Health state utility values on a scale where 1 = full health, 0 = death, and negative values = states worse than death
How it works
The EQ-5D-Y-3L value set for Slovenia was derived using a discrete-choice experiment (DCE) with 1074 adults who evaluated health states by assuming the perspective of a 10-year-old child. The value of the worst health state (33333) was anchored using 200 composite time trade-off (cTTO) interviews. A mixed logit model was used to estimate the coefficients, all of which were statistically significant and showed expected negative signs. Pain/discomfort had the largest impact on health state valuation, followed by anxiety/depression, usual activities, mobility, and self-care.
- Project
- IMPACT HTA
- Funding
- Horizon 2020
- Project status
- Completed 2021
- HTA domains
- Costs & Economic Evaluation
- Categories
- HRQoL
- Technology
- Non-specific
- Assumptions
- Adults can accurately proxy the health state preferences of a 10-year-old child; the latent scale in DCE data is corrected using cTTO anchoring; health state values are transferable across populations with similar cultural context
- Strengths
- First EQ-5D-Y-3L value set published globally; follows international valuation protocol; large, representative sample; uses both DCE and cTTO methods; robust statistical modeling with mixed logit approach
- Limitations
- Relies on adult proxy valuation rather than child self-report; online survey may introduce selection bias; cultural specificity limits generalizability to other countries
- Geographic & clinical scope
- Germany; Slovenia; Spain
- Also known as
- EQ-5D-Y value set for Slovenia, EQ-5D-Y-3L Slovenia value set
Questions this answers
- › How do different health problems affect the quality of life of children in Slovenia?
- › How can we calculate QALYs for children using the EQ-5D-Y-3L instrument?
- › Which health dimensions matter most to children's quality of life according to adult proxies?
- › What is the value of full health versus different levels of health problems in children?
- › How was the worst possible health state valued in this study?
- › Can this value set be used in economic evaluations involving children?
Related methods
Similar by meaning
Beta record. Generated from the primary source via AI extraction and independent audit, pending final human review.